Certified Tissue Bank Specialist (CTBS) Practice Test 2025 – 400 Free Practice Questions to Pass the Exam

The correct answer highlights that Chagas Disease is the exception when considering which RCDAD (Relevant Communicable Disease Agents and Diseases) applies to all tissue donors.

Chagas Disease, caused by the parasite Trypanosoma cruzi, is not a universal screening requirement for all tissue donors like the other listed diseases. This is largely due to the geographical prevalence of Chagas Disease, which is primarily found in regions of South and Central America, and therefore the risk of transmission through tissue donation is lower in regions where the disease is not endemic.

In contrast, the other diseases mentioned—HIV 1/2, HBV (Hepatitis B Virus), and Human TSE (Transmissible Spongiform Encephalopathies)—are significant universal concerns for all tissue donors regardless of geographical considerations. These infections pose a risk of transmission that justifies stringent screening protocols for donors, making them relevant to all tissue donations.